Khan Shaykhun chemical attack

The strike was requested by America's partners "who had identified the target location as an ISIS fighting position," U.S. Central Command said Thursday.

"The world's two foremost nuclear powers cannot cannot have this kind of relationship," Secretary of State Rex Tillerson said after meeting with Russian President Vladimir Putin on Wednesday.

The White House released a declassified report on the attack in Khan Shaykhun. It says the U.S. is "confident" Syria's Bashar Assad was responsible and that Russia is attempting to deflect blame.

In the middle of an international debate about Syria, Bashar Assad, Russia and Iran, Trump press secretary Sean Spicer made an ill-conceived, ahistorical reference to Hitler. He later apologized.

The U.S. has now bombed both main players in the Syrian war: President Bashar Assad's military and the Islamic State. But the Trump administration hasn't spelled out what sort of outcome it's seeking.

The strike leaves more questions than answers — like how it squares with Trump's "America First" policy, does this mean a change in U.S. approach toward Syria and Russia, and what's next?

Russia had been giving President Trump the soft touch. But following the U.S. missile strike on Syria, hopes for friendlier relations are fizzling and the Kremlin's rhetorical cease-fire is over.

"Our feelings today are mixed between happiness and sadness," a Syrian woman tells NPR. "We're tired inside. We're tired of planes. We want to live a normal life."

From Iran to China, from France to Bolivia, see where the world is coming down on the U.S. missile strike on a Syrian air base.

Russia blamed the strike on "speculations on children's photos." At the U.N., Ambassador Nikki Haley said, "The moral stain of the Assad regime could no longer go unanswered."