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In his decision, Judge John Bates said he believed health insurance giant Aetna had tried to leverage its original support for Obamacare to get federal approval for its acquisition of rival Humana.
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Competition on some exchanges will be diminished next year when three of the nation's largest health insurers drop out. Still, most marketplace consumers won't see any ill effects from the moves.
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A July letter from Aetna CEO Mark Bertolini to the Justice Department said the company would pull back from health insurance exchanges if the government opposed the company's merger with Humana.
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The Justice Department says proposed deals between Aetna and Humana as well as Anthem and Cigna would increase the cost of medical care for Americans. The deals are worth a combined $91 billion.